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4 edition of Low dose irradiation and biological defense mechanisms found in the catalog.

Low dose irradiation and biological defense mechanisms

proceedings of the International Conference on Low Dose Irradiation and Biological Defense Mechanisms, Kyoto, Japan, 12-16 July 1992

by International Conference on Low Dose Irradiation and Biological Defense Mechanisms (1992 Kyoto, Japan)

  • 173 Want to read
  • 18 Currently reading

Published by Excerta Medica in Amsterdam, New York .
Written in English

    Subjects:
  • Low-level radiation -- Physiological effect -- Congresses.,
  • Low-level radiation -- Health aspects -- Congresses.,
  • Dose-Response Relationship, Radiation -- congresses.,
  • Immunity -- radiation effects -- congresses.,
  • Radiation Effects -- congresses.,
  • Radiation, Ionizing -- congresses.

  • Edition Notes

    Includes bibliographical references and index.

    Statementeditors, Tsutomu Sugahara, Leonard A. Sagan, Takashi Aoyama.
    SeriesInternational congress series ;, no. 1013
    ContributionsSugahara, Tsutomu., Sagan, Leonard A., Aoyama, Takashi.
    Classifications
    LC ClassificationsRA569 .I435 1992
    The Physical Object
    Paginationxvi, 510 p. :
    Number of Pages510
    ID Numbers
    Open LibraryOL1741815M
    ISBN 100444894098
    LC Control Number92048768

    of stem cells. At low radiation doses, there may be a great deal of incident radiation per cell but the fre-quency of interactions is extremely low. UNSCEAR estimates that a low radiation dose (e.g. 1 mSv per annum) will produce, on average, circa one interac-tion per cell in a year. The human cell contains 46 chromosomes (b)File Size: KB. A measure of the overall risk arising from the irradiation of biologic tissue and organs. Effective Dose Limiting System A set of numeric dose limits that are based on calculations of the various risks of cancer and genetic effects to tissues or organs exposed to radiation. Many reports about the biological effects of the Fukushima nuclear accident on various wild organisms have accumulated in recent years. Results from field-based laboratory experiments using the pale grass blue butterfly have clearly demonstrated that this butterfly is highly sensitive to “low-dose” internal exposure from field-contaminated host-plant by: 3. /books books Thomas Telford Publishing /heoldrcotc Health effects of low dose radiation Health effects of low dose radiation Challenges of the 21st century Thomas Telford Publishing British Nuclear Energy Society, unless other wise stated /heoldrcotc LOW DOSE RADIATION EFFECTS ON THE .

      "The combination of low-dose irradiation and correct gene copy will accelerate our ability to model human disease using stem cells from patients with .


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Low dose irradiation and biological defense mechanisms by International Conference on Low Dose Irradiation and Biological Defense Mechanisms (1992 Kyoto, Japan) Download PDF EPUB FB2

Low Dose Irradiation and Biological Defense Mechanisms: Proceedings of the International Conference on Low Dose Irradiation and Biological Defense M (International Congress Series): Medicine & Health Science Books @ Get this from a library.

Low dose irradiation and biological defense mechanisms: proceedings of the International Conference on Low Dose Irradiation and Biological Defense Mechanisms, Low dose irradiation and biological defense mechanisms book, Japan, July [Tsutomu Sugahara; Leonard A Sagan; Takashi Aoyama;].

A/AC/R/Rev.1, on the biological mechanisms of radiation actions at low doses. Because the document would be of wider interest, the Committee requested the secretariat to investigate means to issue it as a public document on its Size: KB. I was not invited to the second International Conference in Frankfurt, Germany, in Nor was I one of the participants of the International Conference on Low Dose Irradiation and Biological Defense Mechanisms, Kyoto, I attended as a speaker at an adjunct meeting held in Kyoto during that by: 2.

P-2b 1 Activation of Chemical Biological Defense Mechanisms and Remission of Vital Oxidative Injury by Low Dose Radiation a1, 2 and 3 1Okayama University Medical School, OkayamaJapan, 2Central Research Institute of Electric Power Industry, TokyoJapan, 3Science University of Tokyo, Chiba.

LOW DOSE RADIATION AND IMMUNITY. Stimulation of immunity by low dose radiation is manifested in various aspects.

Table 1 shows the immunologic parameters studied in the author's laboratory demonstrating up-regulation of immune functions in animal models exposed to single as well chronic irradiation(24–36) As illustrated in this table, most immunologic parameters are Cited by: Ikushima T () Involvement of induction of specific gene expression by low doses of ionizing radiation.

In: Sugahara T, Sagan LA, Aoyama T (eds) Low dose irradiation and biological defense mechanisms. Elsevier Science, Amsterdam, pp – Google ScholarAuthor: Masami Watanabe, Tsutomu Sugahara.

Low-dose Irradiation and Biological Defense Mechanisms. Elsevier Science; Amsterdam: Sun YM, Liu SZ. Changes in mRNA level of TNFa and IL-1b in peritoneal macrophages of mice after whole-body X-irradiation.

Radiat Proc. ; – Sun YM, Liu SZ. Changes Low dose irradiation and biological defense mechanisms book TNF alpha expression in mouse peritoneal macrophages after whole-body X.

Health Risks of Low Dose Ionizing Radiation in Humans: A Review Sagan L, Aoyama T, Eds. Low Dose Irradiation and Biological Defense.

Dose. This book examines the influence of dose rate and magnitude on the genetic and carcinogenic effects of radiation exposure in animals and man. It systematically examines a broad range of biological effects in simple systems, plants, laboratory animals, and man with special attention given to the effects of prenatal irradiation, changes in life span, and tumorigenesis.

For example, one-third of the most recent UNSCEAR report is devoted to adaptive responses to radiation in cells and organisms (UNSCEAR, ).

Finally, a recent international meeting in Kyoto was devoted to examining evidence for biological defense mechanisms in response to low-dose Low dose irradiation and biological defense mechanisms book to ionizing radiation (Sugahara, et al., ).

The NCRP Annual Meeting was entitled Low Dose and Low Dose-Rate Radiation Effects and Low dose irradiation and biological defense mechanisms book (NCRP, a). In December NCRP held a workshop that involved 30 participants with expertise. Yamada, S., Nemoto, K., Ogawa, Y., Yakatou, Y., Hosi, A.

and Sakamoto; K.() Anti-tumor effect of low dose total (or half) body irradiation and changes of the functional subset of peripheral blood lymphocytes in nonHodgkin’ s lymphoma patients after TBI (HBI),in T.

Sugahara, L. Sagan and Low dose irradiation and biological defense mechanisms book. Aoyama (eds.) Low Dose Irradiation and Biological. “Cellular and Subcellular Alterations in Immune Cells Induced by Chronic, Intermittent Exposure in Vivo to Very Low Doses of Ionizing Radiation and Its Ameliorating Effects on Progression of Autoimmune Disease and Mammary Tumor Growth,” in Low Dose Irradiation and Biological Defense Mechanisms, eds.

Sugahara, L.A. Sagan, and T. Aoyama. As regards to the DNA repair process, resulting effect of the low-dose exposure might be explained by the balance between the rates of DNA damage, which rise linearly with the dose, and mechanisms responsible for cell defense, which are more efficient at low-dose irradiation and become less efficient with an increasing dose.

In general, the Cited by: 2. and experimental data on low dose radiation effects which support the concept of radiation hormesis. These reports point to the possibility of existence of a threshold dose in cancer induction by ionizing radiation and in some cases the occurrence of hormetic effects with stimulation of host defense mechanisms.

The possibility. Induction of hormesis and adaptive responses by low dose radiation have been extensively studied (Wang et al., ). Pre-exposure of diabetic prone mice to low dose radiation (LDR) has reduced the incidence of alloxan diabetes and delayed the onset of hyperglycemia, although the mechanisms are unclear (Wang et al., ).

International Conference on Low Dose Irradiation and Biological Defense Mechanisms Kyoto, Japan, JulyOver the past fifty years, toxicologists and risk assessors have adopted the practice of predicting risks at low levels of exposure on the basis of extrapolating from observations at high levels of exposure, whether in human studies or.

We have shown that cell lethality actually measured after exposure to low-doses of low-LET radiation, is markedly enhanced relative to the cell lethality previously expected by extrapolation of the high-dose cell-killing response.

Net cancer risk is a balance between cell transformation and cell kill and such enhanced lethality may more than compensate for Author: Peter J. Johnston, George D. Wilson. Radiation hormesis is the hypothesis that low doses of ionizing radiation (within the region of and just above natural background levels) are beneficial, stimulating the activation of repair mechanisms that protect against disease, that are not activated in absence of ionizing radiation (similar to vaccinations).The reserve repair mechanisms are hypothesized to be sufficiently.

Low-dose Irradiation Therapy Cures Gas Gangrene Infections by Jerry M. Cuttler Seventy years ago, low-level radiation successfully cured gangrene and other lethal infections, without requiring amputation.

It should be reinstated as a treatment. A drawing of grapeshot wounds to. -- Please note: ***Articles are Free with membership*** This article explores the Biological Effects of using ionizing radiation on humans to make radiographs. Those principles and mechanisms of radiation injury and damage to human tissues are discussed.

This article also reviews those late effects (carginogenesis and genetic effects) cause by low dose occupational exposures to. Biological Response to Low-Dose Irradiation. Low-dose irradiation induces various stimulating effects, especially the activation of biological defense system such as antioxidative [1–9] and immune functions [9, 10].

For example, low-dose irradiation increases Cited by: 4. Inconvenient Low Dose Radiation Science Axed Under Obama Administration. We absolutely need to really understand the biological effects of low doses of ionizing radiation.

There is too much at. 4 AFRRI Programs, Research, and Resources. This chapter addresses the second element of the committee’s statement of task, assessing how Armed Forces Radiobiology Research Institute (AFRRI) programs are advancing research in radiobiological science related to human health risks from exposures to low-dose ionizing radiation.

Interestingly, recent animal and human research has shown that a short-term, subtoxic production of reactive oxygen species (possibly such as that caused by low-dose radiation) has a central role in the mechanisms triggering ischaemic pre-conditioning.

11 This short oxidative burst would trigger protective mechanisms, including up-regulation of Cited by: HEALTH EFFECTS OF LOW LEVEL RADIATION Sadao Hattori On the last chapter of the second book published inhe summarized his opinion by a ().Procrrdings of the International Congerence on Low-Dose Irradiation and Biological Defense Mechanisms,Kyoto,Japan, July,(ra,and.

Biological effects of low-dose ionizing radiation (IR) have been unclear until now. Saliva, because of the ease of collection, could be valuable in studying low-dose IR effects by means of surface-enhanced Raman spectroscopy (SERS).

The objective of our study was to compare the salivary SER spectra recorded before and after low-dose IR exposure in the case of pediatric patients Cited by: 1. Effectiveness of Gene Editing in Human Stem Cells Improves Tenfold Using New Technique.

Contact: Cara Martinez | Email: [email protected] Los Angeles - J – For the first time, researchers have employed a gene-editing technique involving low-dose irradiation to edit the genome of patient stem cells, according to a study published in the.

RSSC BIOLOGICAL EFFECTS OF IONIZING RADIATION 08/11 organs, are of moderately high sensitivity; in terms of injury from large doses of whole-body external radiation, the epithelial cells which line the gastrointestinal tract are often of particular importance.

Cells of low sensitivity include muscle and nerve,File Size: KB. In the FDA approved the use of low-dose ionizing radiation to eliminate pathogens in red meat. This food processing technology can improve the safety of food and extend the shelf life of certain foods by eliminating pathogenic bacteria, parasites, and other microorganisms that cause food-borne s: 1.

@article{osti_, title = {Cellular and molecular research to reduce uncertainties in estimates of health effects from low-level radiation}, author = {Elkind, M M and Bedford, J and Benjamin, S A and Waldren, C A and Gotchy, R L}, abstractNote = {A study was undertaken by five radiation scientists to examine the feasibility of reducing the uncertainties in the estimation.

”Anti-tumor effect of low dose total (or half) body irradiation and changes in the functional subset of peripheral blood lymphocytes in non- Hodgkin's lymphoma patients after TBI (HBI), Low Dose Irradiation and Biological Defense Mechanisms,” Kyoto, July, in Excerpta Medica, Eds.

Sugahara, L.A. Sagan, and T. Aoyama (Amstsrdam. An Open Letter to Advisory Bodies Regarding Low-Dose Total Body Irradiation for Systemic Treatment of Cancer. Dear Colleagues, Though adjuvant chemotherapy has been a standard of practice in the systemic treatment of many cancers, its adverse side effects are of considerable concern.

The effects of low-dose radiation are being increasingly investigated in biological, epidemiological, and clinical studies. Many recent studies have indicated the beneficial effects of low doses of radiation, whereas some studies have suggested harmful effects even at low doses.

This review article introduces various studies reporting both the beneficial and harmful effects of low-dose Cited by: Mechanism of action for anti-radiation vaccine in reducing the biological impact of high-dose gamma irradiation Vladislav Maliev a, Dmitri Popov b, Jeffrey A.

Jones c, Rachael C. Casey d a Vladicaucasian Scientific Center of Russian Academy of Sciences, Biotechnology Dept., 93 pr. Kosta Hetagyrova, Vladicaucas North Ossetia–Alania [Email: [email protected]]Cited by: 7. Effective dose is a dose quantity in the International Commission on Radiological Protection (ICRP) system of radiological protection.

It is the tissue-weighted sum of the equivalent doses in all specified tissues and organs of the human body and represents the stochastic health risk to the whole body, which is the probability of cancer induction and genetic effects, of low levels of.

Exposure of rodents to low-dose whole-body irradiation could cause various antioxidant mechanisms that defend cells from oxidative stress. However, there is a lack of results on antioxidant status in organs of chicken after low dose eggs or whole-body irradiation.

This study was performed to investigate the effect of low-dose gamma-irradiation upon activity of Cited by: 2. Health effects of low dose radiation This book examines the current state of our knowledge about the health effects of radiation and looks forward to exciting developments in our understanding of the mechanisms of radiation's interaction with biological systems and the magnitude of the risks as the twenty-first century approaches.

Low reactive level laser therapy (LLLT) and photobiomodulation are mainly focused on the activation of intracellular or extracellular photoabsorbable molecule (chromophore) and the initiation of cellular signaling using low power lasers and lights. Over the past 40 decades, a number of basic and clinical researches were reported that the laser therapy had the potential Cited by: 1.

Table I Recorded dose rate of recent NASA space programs (Cucinotta ) I.C Pdf Designs of Low Dose Rate Irradiation Facilities Although the linear non-threshold model is a widely accepted hypothesis in current radiation protection practices, the biological effects of prolonged exposure due to low-dose radiation are not well understood.Radiations of high linear energy transfer (LET) have long been known to download pdf greater biological effec-tiveness per unit dose than those of low LET, for a wide variety of biological effects.

However, values of relative biological effectiveness depend considerably on the biological system and in some instances the values are clearly below Size: KB.Cellular Defense Mechanisms Against the Biological Effects ebook Ionizing Radiation Eye-Opener E Douglas R.

Boreham Biological Defense Mechanisms Against the Effects of High Doses of Ionizing Radiation Biological Response Mechanisms Against the Effects of Low Doses of Ionizing by prior sublethal low priming dose of radiation.